April is Mathematics and Statistics Awareness Month. This is a time to increase understanding and appreciation of mathematics and statistics. Both subjects play a significant role in addressing many real-world problems. Research in mathematics and statistics is ongoing, revealing new results and applications everyday.
Please join us in our celebration!
Math and Stat Awareness Month Events for April 2017
This is a nontechnical lecture. You will understand this!
An Introduction to Early Stage Clinical Trial Design
Dr. Daniel Zelterman
4:00 Thursday, 6 April 2017
Oliver Hall Auditorium (112)
Refreshments at 3:30 in the lobby.
Abstract: We are familiar with the large randomized clinical trials reported in the news. But these Phase III trials are the culmination of many smaller studies which are also of interest. In Phase I trials, we seek an estimated safe dose of the drug to be administered to patients with a low probability of toxic side-effects. From a statistical point of view, how should such experiments be conducted? In Phase II trials we want to show a treatment effect when compared to a historical control group. In Phase II we also want to avoid treating patients with an inferior treatment so we may include an early stopping rule. We will talk about the challenges available to statisticians in designing these experiments.
Daniel Zelterman, PhD, is Professor of Epidemiology and Public Health in the Division of Biostatistics at Yale University. Before moving to Yale in 1995, he was on the faculty of the University of Minnesota and the University at Albany. He is an elected Fellow of the American Statistical Association and serves as an Associate Editor of Biometrics and several other statistical journals.
Dr. Zelterman works in areas of applied statistics motivated by intriguing questions posed in a variety of scientific areas. He works closely with researchers in other disciplines, chiefly cancer and HIV. His work involves the design of clinical trials, experiments, and surveys, with particular emphasis on the identification of clear and relevant endpoints in such applications. He is also involved in the analysis and interpretation of the results of these investigations. He is the author of six books on statistics and statistical methods, incorporating SAS and R software.
In his spare time, Dr. Zelterman plays the bassoon in several amateur chamber and orchestral groups in the New Haven area. He has backpacked hundreds of miles of the Appalachian Trail.
On-line problem solving competition
We will post sets of problems accessible from this web page at the beginning of April. Participants will have two week to formulate and submit solutions to the problems. There will be problem sets at several levels ranging from the middle school level to the graduate school level.
All participants will be acknowledged. Modest prizes will be awarded to several of the participants who do well on the problems. Details will be added soon.