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Louisiana ASA Chapter

Louisiana Chapter of the American Statistical Association

Spring 2017 Meeting

View the Titles and Abstracts here.  The schedule will be posted very soon.

The Spring 2017 chapter meeting will be held on Friday, 7 April 2017, on the University of Louisiana at Lafayette campus in Lafayette. Our keynote speaker is Daniel Zelterman of Yale University.  He will speak on Thursday afternoon, 6 April 2017, as part of our celebration of mathematics and statistics awareness month and on Friday at our meeting.  If you can make it to the Thursday presentation you are invited to join us for dinner Thursday evening. (Let Calvin know if you plan to come to dinner.)

Introduction to Early Stage Clinical Trial Design (Daniel Zelterman's Thursday afternoon talk)

4:00 Thursday, 6 April 2017
Oliver Hall Auditorium (112)

Refreshments at 3:30 in the lobby.

We are familiar with the large randomized clinical trials reported in the news.  But these Phase III trials are the culmination of many smaller studies which are also of interest.  In Phase I trials, we seek an estimated safe dose of the drug to be administered to patients with a low probability of toxic side-effects.  From a statistical point of view, how should such experiments be conducted? In Phase II trials we want to show a treatment effect when compared to a historical control group.  In Phase II we also want to avoid treating patients with an inferior treatment so we may include an early stopping rule.  We will talk about the challenges available to statisticians in designing these experiments.


Distributions Associated with Simultaneous Multiple Hypothesis Testing (Daniel Zelterman's Friday morning talk)

We develop a distribution to describe the number of hypotheses found to be statistically significant using the rule from Benjamini and Hochberg (1995) for controlling the false discovery rate (FDR). This distribution has both a small sample form and an asymptotic expression for testing many independent hypotheses simultaneously. We describe a distribution to approximate the marginal distribution of p-values under the alternative hypothesis.  This distribution is useful when there are many different alternative hypotheses and these are not individually well understood. We use the approximating distribution to estimate the fraction of p-values sampled under the null and multiple alternative hypotheses in two numerical examples.

Daniel Zelterman, PhD, is Professor of Epidemiology and Public Health in the Division of Biostatistics at Yale University. Before moving to Yale in 1995, he was on the faculty of the University of Minnesota and the University at Albany. He is an elected Fellow of the American Statistical Association and serves as an Associate Editor of Biometrics and several other statistical journals.

Dr. Zelterman works in areas of applied statistics motivated by intriguing questions posed in a variety of scientific areas. He works closely with researchers in other disciplines, chiefly cancer and HIV. His work involves the design of  clinical trials, experiments, and surveys, with particular emphasis on the identification of clear and relevant endpoints in such applications. He is also involved in the analysis and interpretation of the results of these investigations.  He is the author of six books on statistics and statistical methods, incorporating SAS and R software.

In his spare time, Dr. Zelterman plays the bassoon in several amateur chamber and orchestral groups in the New Haven area. He has backpacked hundreds of miles of the Appalachian Trail.


The Chapter meeting on Friday will be held in Mouton Hall (morning session) and Maxim Doucet Hall (afternoon session).  The approximate time is 9-4 or 9-5.

Further details about the meeting will be posted here as they become available.

 


Spring 2017 Student Research Competition

The Spring 2017 Student Research Competition will be held, in conjunction with the Spring meeting, on Friday, 7 April 2017, on the University of Louisiana at Lafayette campus in Lafayette.

Visit the Student Research Competition webpage for details.


2017 Chapter Officers

President:

BeiBei Guo
Department of Experimental Statistics
Room 61 Martin D. Woodin Hall
Louisiana State University
Baton Rouge, LA 70803-5606
beibeiguo@lsu.edu

Vice President:

Sungsu Kim
Mathematics Department
University of Louisiana at Lafayette
Box 43568
Lafayette, LA 70504-3568
sungsu@louisiana.edu

Secretary/Treasurer:

Evrim Oral
Biostatistics Section
LSUHSC School of Public Health
2020 Gravier Street, 3rd Floor
New Orleans, LA 70112
eoral@lsuhsc.edu

Chapter Representative:

Kalimuthu Krishnamoorthy
Mathematics Department
University of Louisiana at Lafayette
Box 43568
Lafayette, LA 70504-3568
krishna@louisiana.edu

If you have any suggestions regarding the chapter such as: proposals for activities, potential speakers, or the like, please send them to the president.